ELISA is an abbreviation for "enzyme-linked immunosorbent assay. It also involves an antibody or antigen immunologic molecules. Examples of the uses of an ELISA test includes to diagnose infections such as HIV human immunodeficiency virus and some allergic diseases like food allergies.
This process is expected to lead to revised recommendations from SAGE in Apriland to an updated WHO position paper on dengue vaccine thereafter.
WHO Secretariat recommends that the July position paper be read in conjunction with this document. This document replaces a questions and answers document web-posted by WHO on 30 November Dengue is a febrile illness caused by a mosquito-borne virus, for which there is no specific anti-viral treatment.
Many dengue virus infections produce no or only mild clinical symptoms i.
The global annual incidence of clinically apparent dengue has been estimated at about million cases, predominantly in Asia, followed by Latin America and to a lesser extent Africa.
Dengue may be caused by any one of four dengue viruses serotypes In most cases, dengue is a self -limiting illness, but may require hospital admission, where supportive care can modify the course of the illness.
Recovery from infection by one serotype is thought to provide lifelong immunity against that particular serotype, but susceptibility remains to the other 3 and hence a person can be infected by up to four serotypes during his or her lifetime.
After infection with one serotype, cross-immunity provides temporary partial protection against the other serotypes. There is a small risk of severe disease after any dengue infection, but the second infection by a different serotype to the first is thought to be associated with the highest risk of severe dengue, while the third and fourth infections are usually associated with a milder clinical course.
What is severe dengue?
Severe dengue is a relatively rare but serious complication following dengue infection due to plasma leaking, fluid accumulation, respiratory distress, severe bleeding or organ impairment. What is dengue serostatus?
Serostatus refers to whether a person has experienced a dengue infection in the past. A seronegative individual has not had a previous dengue infection. A seropositive individual has had a previous dengue infection with at least one serotype.
A person may not know whether he or she was infected in the past, because many dengue infections are clinically inapparent. Among those who are seropositive, some individuals will only have been infected with one dengue serotype and these individuals are at higher risk of severe dengue when infected with a second dengue serotype.
Of note, only few secondary infections will lead to severe disease. The vaccine has 4 components, encoding for antigens of the four dengue virus strains. Dengvaxia is the first dengue vaccine to be licensed. Licensure means that a national regulatory authority reviewed all of the data on the vaccine, found that the benefits outweigh the risks, and permitted the company to have a marketing authorization to sell the product in that country.Discuss the answers to these with others in the class.
Ask for help if you're not sure about the answers. What are these ELISA experiments designed to enable you to determine about your rabbit immunoglobulin samples?
Question. Asked 3 years ago.
Ho Lun Kar. National Yang Ming University; Can someone answer two questions about ELISA? All Answers (6) 3 years ago. Gertrudis Rojas.
Center of Molecular Immunology. Read 7 answers by scientists with 2 recommendations from their colleagues to the question asked by Rohail Jawed on Jan 11, ELISA is a test that detects and measures antibodies in your blood. It's used to determine if you have antibodies related to certain infectious conditions.
It is important that you consider these medical options as you decide whether to seek counseling and testing for HIV infection. Deciding whether to seek counseling and testing can be very hard. Eric from Graduateway Hi there, would you like to get an essay?
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